prevalence of cryptosporidium infection in immunocompromised pa-tients, in south-west of iran, 2009-10

نویسندگان

a balouty dehkordy department of myco-parasitology, faculty of medicine, jundishapur university of medical sciences, ahvaz, iran

a rafiei department of myco-parasitology, faculty of medicine, jundishapur university of medical sciences, ahvaz, iran and infectious diseases and tropical medicine research center, faculty of medicine, jundishapur university of medical sciences, ahvaz, iran

sm alavi infectious diseases and tropical medicine research center, faculty of medicine, jundishapur university of medical sciences, ahvaz, iran

sm latifi statistic and epidemiology department, faculty of public health, jundishapur university of medical sciences, ahvaz, iran

چکیده

background: cryptosporidium is a protozoan parasite with worldwide distribution. the aim of this study was to estimate the prevalence of cryptosporidium infection by antigen detection in faeces among immunocompromised patients referred to educational hospitals of ahvaz city, south-west of iran, 2009-2010. methods : fecal samples from 176 immunocompromised patients were collected and cryptosporid­ium coproantigen test was performed using elisa method (drg kit, germany). a questionnaire was completed for each case and the results were analyzed using descriptive and chi-square tests, by spss statistical software (15 th version). results: our study indicated 5.1% cryptosporidium infection prevalence in the immunocompro­mised participated population. furthermore, 4.2 %, 4%, 4.5 % and 9.1% infection rates were identi­fied in children suffered from hematopoietic malignancy, adult cancer patients, renal trans­plant recipients, and hiv + cases, respectively. there was not significant correlation between the infection and age and gender ( p >0.05).  infection was most frequent among hiv + patients. conclusion : the present study confirmed the high prevalence of cryptosporidium antigen in fe­cal samples of immunocompromised patients in the region. as no chemotherapeutic agents have yet proven, especially in immunosuppressed patients, therefore our results highlight the impor­tance of preventive intervention in these groups.

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Prevalence of Cryptosporidium Infection in Immunocompromised Patients, In South-West of Iran, 2009–10

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عنوان ژورنال:
iranian journal of parasitology

جلد ۵، شماره ۴، صفحات ۴۲-۴۷

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